The Centre for Reproductive Health is the UK’s first fully integrated fertility and women’s health hospital. Designed by consultants and embryologists, this state of the art facility is dedicated to giving patients the best chance of conceiving by using the most advanced infertility techniques and technologies available today.
We believe in offering only scientifically proven techniques, treatments or procedures that could make genuine differences to the outcome for the majority of our patients.
Some of the innovations that we provide:
Pre-implantation genetic testing (PGT-A)
PGT-A is a technique used during IVF to screen embryos for any abnormalities in their genetic material (chromosomes). Recent research has suggested that IVF success rates may be improved if embryos are first screened for chromosomal abnormalities and embryos with the correct number of chromosomes transferred back. Most abnormal embryos would either fail to implant in the womb or miscarry during pregnancy. It is potentially suitable for anyone undergoing IVF treatment but may be of particular benefit for women over the age of 35, in cases where there have been several failed cycles of IVF already (recurrent implantation failure) or recurrent miscarriages, where there is a known family history of chromosomal problems or the male partner’s sperm has been identified as containing a high number of chromosomal abnormalities. Although there is not yet research to confirm that PGT-A increases your overall chances of having a baby, there is evidence that it may help to reduce the likelihood of having a miscarriage. For more information, please see the HFEA website or speak to a member of staff.
Embryos created through IVF treatment have traditionally been transferred back into the womb 2 or 3 days after fertilisation. It is now possible, however, to allow an embryo to develop for 5-6 days before transfer, to the stage where it is known as a ‘blastocyst’. At this more mature stage of development, it is easier for embryologists to distinguish good quality embryos from poorer quality ones which may have slowed in their growth or stop developing altogether, and thus transfer back those with the best chance of creating a successful pregnancy.
In a small number of cases embryos are unable to implant because of the quality of the lining of the womb. Endometrial scratching is a procedure that is available to some patients who have previously experienced embryo implantation failure. It involves your endometrial lining being ‘scratched’ using simple equipment before your IVF cycle starts. It is a simple and quick procedure, with minimal risk of complications, similar to undergoing a smear test. The theory is that this procedure triggers the body to repair the site of the scratch, releasing chemicals and hormones that make the womb lining more receptive to any embryos which are later transferred. Some studies suggest the treatment may activate genes that make the womb lining more receptive to an embryo implanting. Although the evidence that endometrial scratching can be beneficial is from a number of small trials there are currently 3 large clinical trials looking at the benefits of endometrial scratching. For more information, please see the HFEA website or speak to a member of staff.
EmbryoGlue is a solution that contains a substance called hyaluronan and has been developed to closely resemble the environment in the uterus at the time of implantation. Studies have shown that placing the embryo in EmbryoGlue prior to embryo transfer may improve the chance of the embryo implanting in the womb. It is not a glue in the common sense, but acts as a glue by increasing the chance of implantation of the embryo to the uterus. Current studies show that using EmbryoGlue increases pregnancy and live birth rates by around 10%. At the Centre for Reproductive Health we use EmbryoGlue routinely for all embryos that are to be transferred either in a fresh or frozen cycle. For more information, please see the HFEA website or speak to a member of staff.
Laser Assisted Hatching
Assisted hatching is a technique sometimes used for IVF and similar procedures. It involves thinning the shell surrounding the embryo (the zona pellucida), or making a hole in it.At the Centre for Reproductive Health this procedure is done using a laser on day 3 when the embryo is at the 6-8 cell stages and then allowing the embryo to continue to develop up to day 5 (blastocyst stage). It is suggested that by making a hole or weakening the zona pellucida by assisted hatching, the embryo may be helped to ‘hatch out of the zona pellucida and improve the chance of the embryo attaching to the lining of the womb. The technique is believed to benefit some patients who have embryos with a thicker zona pellucida. For more information, please see the HFEA website or speak to a member of staff.
Get in touch
If you have a question about any of our services, please call us on 01925 202180 or contact us below.
If you would like to find out more about IVF-Life UK, our facilities or treatments, you can contact us online here. Alternatively, you can call us on 01925 202180, and we will be more than happy to assist you with any other advice.